Quantitative phase imaging for cytology

The Phasics quantitative phase microscopy solution allows analyzing large living-cell populations at the single-cell level. It delivers a comprehensive dataset of accurate quantitative parameters for individual cells such as: morphology (surface, shape factor…), dry mass, and many phase-shift-related parameters (density, homogeneity, proteins distribution... ). Thus it is ideal for multiple assays as an automated image cytometer.

  • Artefact-free images: ensure robust and automated segmentation and measurements
  • Label-free technique: allows long time-lapse microscopy for non-invasive cellular study: motility, proliferation, monitoring of cell cycle, apoptosis, viability, differentiation, cytotoxicity…
  • Merging with fluorescence microscopy: to get a comprehensive dataset at the cellular and molecular level
  • Easy integration to high-content screening platform: provides valuable quantitative data combined with machine learning algorithms to enable automated diagnosis
  • ▽ Measurement setup

    Plug and play Quantitative Phase Imaging camera used in for cytology

    Dry mass and morphometric parameters are proven indicators of many cell mechanisms: viability (apoptosis detection…), cell growth (cell cycle status, proliferation…), and cell differentiation based on phenotypic characteristics. They also reveal cell abnormalities: shape change, heterogeneity, presence of parasites… They are useful parameters to identify and monitor cells in a large population.

    It can be applied to:

    • Cancer cell proliferation & growth rate monitoring
    • Pharmacology research: drug screening, drug discovery, cytotoxicity assays
    • Bioprocess: Cell culture monitoring, microbiology
    • Blood testing: Red blood cell pathology identification such as anemia type identification, parasitemia calculation
    • Stem cell monitoring & selection in regenerative medicine
  • ▽ Applications gallery

    Cell growth and apoptose for cancer reseach

    Bio production and microbiology

    Research

    Blood testing

    Drug testing and toxicology

Advantages

Easy to integrate

  • Easiest QPI technique to integrate
  • Compatible with high-content screening
  • Multi-parametric single-cell classification via artificial intelligence

Highly Reliable Measurement

  • Automated segmentation and analysis 
  • Artefact-free images
  • High-sensitivity phase measurement

Label-Free Imaging

  • No photobleaching
  • Fast protocol
  • Cell monitoring over long period of time

Downloads

Download


Related Products

Related markets

Life science

Related publications

None

Explore Phasics' comprehensive library of scientific publications, featuring the latest advancements. Discover cutting-edge research from both Phasics and our valued customers, driving innovation.

Access Here

Sign up to receive the latest updates and news